Vertebroplasty with artificial bone repairs vertebral compression fractures in the elderly: 3-month follow-up results

doi:10.3969/j.issn.2095-4344.2014.30.026

Abstract

Abstract:

BACKGROUND: Bone cement used in the vertebroplasty treatment of osteoporotic vertebral compression fractures is nonabsorbable and has stronger intensity than normal bone tissue, which can cause further fractures of adjacent segments.
OBJECTIVE: To investigate the short-term effect of vertebroplasty with artificial bone in the treatment of osteoporotic thoracolumbar fractures.
METHODS: A total of 21 patients with osteoporotic vertebral compression fractures were enrolled, including 7 males and 14 females, aged 61-89 years old. All the patients were subjected to vertebroplasty with calcium sulfate injection. Visual analog scale and Oswestry Disability Index assessment were used before and at 0, 24, 48 weeks after treatment; meanwhile, X-ray and CT were used to observe the filling and leakage of artificial bone.
RESULTS AND CONCLUSION: After treatment, all the patients showed improvements in the scores of visual analog scale and Oswestry Disability Index (P < 0.01). X-rays and CT scans showed that there were three cases of leakage but without spinal cord and nerve compressions. After 3 months, most of the artificial bone was absorbed. These findings indicate that vertebroplasty with artificial bone can ease pain and improve living conditions of patients with osteoporotic vertebral compression fractures.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: vertebroplasty, osteoporotic fractures, calcium sulfate

CLC Number:

R318

Zhao Wei-biao, Li Ji, Li Yi, He Zi-wei. Vertebroplasty with artificial bone repairs vertebral compression fractures in the elderly: 3-month follow-up results[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(30): 4917-4920.

Figures/Tables 1

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